Cell facilitated controlled radical polymerisation

该项目旨在通过结合可逆加成断裂链（RAFT）聚合技术和细菌细胞内的氧化还原过程来开发一种可控聚合方法。这种聚合方法将细菌细胞表面的生物信息复制到生长的聚合物结构中。单体结构和官能度的变化将用于控制细胞表面化学物质掺入新聚合物结构中。这种细胞激活的受控聚合可以促进聚合物合成，从而产生生物指示的聚合物模拟物和新的抗菌剂。

This project aims to develop a controlled polymerisation method by combining reversible addition fragmentation chain (RAFT) polymerisation technology and the redox processes within bacterial cells. This polymerisation method will copy biological information in the bacterial cell surface into a growing polymer structure. Variations in the monomer structures and functionality will be used to control the incorporation of cell surface chemistry into the new polymer structure. Such cell-enabled controlled polymerisation could advance polymer synthesis resulting in biologically instructed polymer-mimics and new antibacterial agents.