Structurally Nanoengineered Antimicrobial Polypeptide Particles (SNAPPs)

结构纳米工程抗菌多肽颗粒（SNAPP）

• 批准号: DP160101312
• 负责人: Prof Greg Qiao
• 金额: $ 34.43万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2020-12-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160101312
• 关键词: Structurally; Nanoengineered; Antimicrobial; Polypeptide; Particles

This project aims to develop a new platform technology for the development of antimicrobial agents by combining expertise in polymer science and antimicrobial studies. It aims to develop new nanoengineered particles for combating antibiotic-resistant bacteria, investigate the influence of particle architecture on antibacterial properties, and determine the mechanism of action. This may support the development of antibiotic treatments using new polypeptide particles as antibacterial drugs, resulting in advances in nanobiotechnology, polymer therapeutics and advanced materials. The outcomes may revolutionise the synthetic approach to antimicrobial peptides and contribute significantly towards current antibiotic treatments and approaches for advanced antibacterial formulations.

该项目旨在通过结合聚合物科学和抗菌剂研究的专业知识，为抗菌剂的开发开发一种新的平台技术。它的目的是开发新的纳米工程颗粒来对抗抗生素耐药细菌，研究颗粒结构对抗菌性能的影响，并确定其作用机制。这可能会支持使用新的多肽颗粒作为抗菌药物的抗生素治疗的发展，从而导致纳米生物技术、聚合物疗法和先进材料的进步。这些结果可能会彻底改变抗菌肽的合成方法，并对目前的抗生素治疗和先进抗菌配方的方法做出重大贡献。