The LINK to Regulating Lysine Levels in Wheat

该项目旨在描述最近发现的一种称为“赖氨酸(K)配体诱导结合”（LINK）模型的变构机制。LINK模型调节细菌和植物中一种关键生物合成酶的功能，包括小麦等重要的农业物种。同时，它代表了生物化学领域的一个非常重要的发现。该项目的预期结果包括深入了解调节细胞内赖氨酸水平的新变构机制的分子基础，从长远来看，这为农业效益提供了极好的潜力。

This project aims to characterise a recently discovered allosteric mechanism called 'Ligand-Induced association by Lysine (K)' (LINK) model. LINK model regulates the function of a key biosynthetic enzyme in bacteria and plants, including agriculturally-important species such as wheat. Also, it represents a highly significant discovery to the field of biochemistry. The expected outcomes of this project include an in-depth understanding of the molecular basis of a new allosteric mechanism for regulating intracellular lysine levels, which in the longer term offers excellent potential to be manipulated for agricultural benefits.