CARDIOVASCULAR BEHAVIOR AND THE RELAXATION RESPONSE

本研究提案的目的是更好地定义临床 放松反应的应用和基础生理学， 催眠反应和交感神经系统活动。 关注 将集中在（1）催眠反应的关系，边界 高血压患者的血压变化与 松弛响应的引出，以及这些参数与 脑去甲肾上腺素水平，如尿MHPG测定所示;（2） 放松反应和催眠反应之间的联系 在固定的工作强度下运动时的耗氧量;（3） 通过血浆去甲肾上腺素水平测量交感神经系统反应性 以及通过尿MHPG测定测量的脑去甲肾上腺素水平的变化 这与放松反应的诱发有关， 与催眠反应的关系

The objectives of this research proposal are to define better the clinical applications and underlying physiology of the relaxation response as related to hypnotic responsivity and to sympathetic nervous system activity. Attention will be focused upon (1) the relation of hypnotic responsivity of borderline hypertensive patients to their blood pressure changes associated with elicitation of the relaxation response, and the relation of these parameters to brain norepinephrine levels as indicated by urinary MHPG assay; (2) the relation between elicitation of the relaxation response and hypnotic responsivity to oxygen consumption while exercising at a fixed work intensity; (3) changes in sympathetic nervous system reactivity measured by plasma norepinpehrine levels and changes in brain norepinephrine levels as measured by urinary MHPG assays which are associated with elicitation of the relaxation response and their relation to hypnotic responsivity.