ORGANIZATION OF AUDITORY-MOTOR PATHWAYS IN THE MIDBRAIN

听觉启动的或定向的反应由听觉控制 与运动通路相互作用的信息。需要检验的假设 是中脑的外侧被盖和脑干的峡部 与听觉运动功能密切相关。的具体目标 这项研究的目的是：(1)研究 外侧被盖的传出轴突投射和(2) 听觉和非听觉传入投射的组织 外侧被盖。为了实现这些目标，我们结合了一些实验性的 解剖程序将被用来研究猫和负鼠 脑干--包括放射自显影，HRP逆行运输，以及 用荧光染料进行双重标记。三个被盖之间的联系 将探索的区域：大鼠臂核区域 下丘、外侧丘核及周围网状核 形成，以及中央腹侧和外侧的被盖结构 下丘的核。我们的目标是展示 外侧被盖的组织及其可能的相互作用 听觉-运动通路。这项拟议的研究提供了一个重要的 对理解中脑听觉机制的贡献。

Acoustically-initiated or directed responses are controlled by auditory information interacting with motor pathways. The hypothesis to be tested is that the lateral tegmentum of te midbrain and isthmus of the brainstem is intimately involved in auditory-motor functions. The specific aims of the proposed research are to investigate (1) the origin and termination of efferent axonal projections from the lateral tegmentum and (2) the organization of auditory and nonauditory afferent projections to the lateral tegmentum. To acomplish these aims a combination of experimental anatomical procedures will be used in investigating the cat and opossum brainstem--including autoradiography, retrograde transport of HRP, and double labeling with fluorescent dyes. The connection of three tegmental regions will be explored: the region of the nucleus of the brachium of the inferior colliculus, the lateral lemniscal nuclei and surrounding reticular formation, and the tegmental structures ventral and lateal to the central nucleus of the inferior colliculus. The goals are to demonstrate the organization of the lateral tegmentum and possibly its interaction with auditory-motor pathways. The proposed research offers a significant contribution to understanding midbrain auditory mechanisms.