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INTERNATIONAL WORKSHOP ON HUMAN CHROMOSOME 2

INTERNATIONAL WORKSHOP ON HUMAN CHROMOSOME 2
人类 2 号染色体国际研讨会
批准号:
3435515
负责人:
SUSAN L NAYLOR
金额:
$1.83万
依托单位国家:
美国
项目类别:
财政年份:
1992
资助国家:
美国
项目状态:
已结题
起止时间:
1992-09-25 至 1994-08-31

项目摘要

项目成果

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中文摘要
翻译
2号染色体占人类基因组的7%,包含270兆碱基的 DNA尽管2号染色体很大,但它积累标记的速度一直很慢。 最近,已经产生了大量新的标记 2号染色体,从分配给 2号染色体:HGM9只有50个单拷贝DNA片段, HCM11有134个明确指定的标记。因此,现在我们将 能够开始构建2号染色体的图谱。这样做的目的 研讨会的目的是整合来自多个实验室的数据,以构建 2号染色体的连锁和辐射图谱。这些图谱将建立 地图的公共基础,识别重叠,并识别 需要解决问题。研讨会将于1992年11月举行,为期两天。 (在美国人类遗传学学会之前)在旧金山。 会议的结构将是一系列简短的演讲,由 每个参与的实验室随后都要进行紧张的工作 解决地图中的不一致之处,并产生协商一致的地图。
英文摘要
Chromosome 2 is 7% of the human genome and encompasses 270 megabases of DNA. Despite its size, chromosome 2 has been slow to accumulate markers. Recently, a large number of new markers have been generated for chromosome 2, as evidenced by the number of DNA segments assigned to chromosome 2: at HGM9 there were only 50 single copy DNA segments and at HCM11 there were 134 firmly assigned markers. Consequently, now we will be able to begin to construct maps for chromosome 2. The purpose of this workshop is to consolidate data from many labs to construct physical, linkage and radiation maps for chromosome 2. These maps will establish the common bases for the maps, identify overlap, and identify areas that need resolution. The workshop will be two days in November, 1992 (preceding the American Society of Human Genetics) in San Francisco. The structure of the meeting will be a series of short presentations by each of the laboratories involved followed by an intense working session to resolve inconsistencies in the map and to produce consensus maps.
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