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GENOMICS SHARED RESOURCE

基因组学共享资源

基本信息

批准号：
8637193
负责人：
SUSAN L NAYLOR
金额：
$ 1.74万
依托单位：
UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-08-01 至 2014-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8637193
关键词：
Acids Aliquot Anticoagulants Arabidopsis Aspirate substance Biological Assay Biological Markers Blood Blood specimen Bone Marrow Caenorhabditis elegans Cancer Center Canis familiaris Cattle Cell Line Cells Chickens Citrates Consult Culture Media Cultured Cells Custom Cytogenetics Shared Resource DNA DNA copy number Data Data Quality Databases Diagnosis Diagnostic Neoplasm Staging Discrimination Drosophila genus Experimental Designs Fluorochrome Freezing Funding Gene Deletion Gene Dosage Gene Expression Gene Expression Microarray Analysis Gene Expression Profiling Genes Genetic Genetic Polymorphism Genome Genomics Genomics Shared Resource Genotype Glucose Human Human Genome Human Herpesvirus 4 Industry Label Length Lymphocyte Macaca mulatta Maize Manuals Messenger RNA Methodology Methods MicroRNAs Microarray Analysis Microarray Shared Resource Molecular Molecular Genetics Molecular Profiling Mononuclear Mononuclear Leukocytes Mus NCI Center for Cancer Research Nucleic Acids Oligonucleotides Peripheral Blood Mononuclear Cell Primer Extension Process Promega Protocols documentation RNA Rana Rattus Reader Relative (related person)Reproducibility Research Personnel Resource Sharing Rice Running Sampling Services Single Nucleotide Polymorphism Solid Neoplasm Source Specimen Speed Technical Expertise Technology Testing Time Tube Tumor Cell Line Tumor Tissue Venous Vial device Viral Whole Blood Yeasts Zebrafish anticancer research base cancer cell cancer therapy comparative genomic hybridization congenic cost cyanine dye 5 density experience genetic technology immortalized cell instrument interest lymphoblastoid cell line member neoplastic cell peripheral blood research study sex tissue culture tissue/cell culture trizol tumor

项目摘要

The Genomics Shared Resource provides state-of-the-art services to the members of the Cancer Center by providing access to two complementary platforms, the lllumina platform, used for primarily for highthroughput genotyping of single nucleotide polymorphisms, and the Agilent Technologies platform, used primarily for array comparative genomic hybridization and expression microarray analysis. In addition to these genomic services, the shared resource offers Cancer Center members assistance in automated nucleic acid isolation, real-time quantitative PCR, and sample banking. The banking of samples range from isolating DNA, processing blood specimens, establishing lymphoblastoid cell lines and long term storage of samples. The shared resource has been reorganized with a single overall coordinator and two co-directors, one per platform. All three have extensive experience in genomics and provide Cancer Center members with consulting services to assist in experimental design. This shared resource combines two previous funded cancer center shared resources, the Cytogenetic and Genetics Shared Resource and the Microarray Shared Resource.

基因组学共享资源通过以下方式为癌症中心成员提供最先进的服务提供对两个互补平台的访问，这两个平台是llLumina平台，主要用于高吞吐量单核苷酸多态基因分型，和安捷伦技术平台，使用主要用于阵列比较基因组杂交和表达微阵列分析。除了……之外这些基因组服务，共享的资源为癌症中心成员提供自动化的帮助核酸提取、实时定量聚合酶链式反应和样本库。样品库的范围从分离DNA，处理血液标本，建立淋巴母细胞系和长期保存样本。共享资源已通过单个总协调人和两个联合董事进行了重新组织，每个平台一个。这三人在基因组学方面都有丰富的经验，并为癌症中心成员提供提供咨询服务，协助进行实验设计。此共享资源结合了以前的两个资助的癌症中心共享资源、细胞遗传学和遗传学共享资源和微阵列共享资源。