CESIUM IRRADIATOR FOR MEDICAL RESEARCH

该申请要求资金购买铯辐照器， 达特茅斯-希区柯克医疗中心的辐照共享服务实验室 中心（DHMC）。 1991年12月，医疗中心将开设一个新的 医院、诊所和医学院，拥有60个实验室，距离 目前的网站。 在接下来的几年里，剩下的 医学院设施将迁往新址。 照射 共享服务将被安置在一个由辐照器组成的套房中， 一间动物饲养室和一间预备实验室。 将 由14名调查人员使用，每个人都有同行审查和资助 在该项目中，样品的辐照对研究至关重要。 这一新设施将取代现有的辐照设施住房 一台通用电气Maxitron-300 X光机，已用于19 年 新设施的使用者将来自以下部门： 生物化学，医学，药理学和毒理学，微生物学， 达特茅斯社区和家庭医学、外科和病理学 医学院 它将继续作为一个共用设施加以管理 诺里斯棉花癌症中心（NCCC）的指导下， 国立中央大学放射生物学研究计画。 当前的日志 1990年，15名研究人员进行了560次辐照， NIH资助的项目。 细菌，化学物质，白细胞，细胞培养物， 啮齿类动物和大型动物都要接受常规辐照。 这位19岁的 我们目前使用的X光机越来越难以维护;它将 不会被重新安置到新的DHMC，并且有重大的技术问题。 铯辐照器的优点，使其能够提供更多 为生物医学研究项目提供适当的辐照。

This application requests funds to purchase a cesium irradiator for the irradiation shared service laboratory at the Dartmouth-Hitchcock Medical Center (DHMC). In December 1991 the medical center will open a new hospital, clinic, and medical school with 60 laboratories 2.5 miles from its current site. Over the next several years, the remainder of the medical school facilities will move to the new site. The Irradiation shared service will be housed in a suite comprised of the irradiator room, an animal holding room, and a preparatory laboratory. It will be used by 14 investigators, each of whom has a peer reviewed and funded project in which irradiation of specimens is critical to the studies. This new facility will replace the existing irradiation facility housing a General Electric Maxitron-300 X-ray machine which has been used for 19 years. Users of the new facility will come from the departments of Biochemistry, Medicine, Pharmacology and Toxicology, Microbiology, Community and Family Medicine, Surgery, and Pathology in the Dartmouth Medical School. It will continue to be administered as a shared facility of the Norris Cotton Cancer Center (NCCC) under the direction of the Radiobiology Research Program of the NCCC. The log of the current facility shows 560 irradiation sessions in 1990 by 15 investigators with NIH-funded projects. Bacteria, chemicals, leukocytes, cell cultures, rodents, and large animals are routinely irradiated. The 19 year-old X-ray machine we currently use is becoming difficult to maintain; it will not be relocated to the new DHMC, and there are significant technical advantages to a cesium irradiator, enabling it to provide more appropriate irradiations for the biomedical research projects.