Combining laboratory and computational approaches to develop reliable low cost HIV prognostics

某些被称为“CCR5拮抗剂”的抗HIV药物阻止HIV进入免疫细胞。然而，艾滋病毒的耐药性可能会发生。在全球范围内，患者获得CCR5拮抗剂的机会有限，因为确定艾滋病毒耐药性所需的治疗前实验室测试既昂贵又耗时。我的研究将导致计算机程序的发展，可靠，快速和廉价地确定艾滋病毒耐药性，从而大大提高全球患者获得CCR5拮抗剂。

Certain anti-HIV drugs called "CCR5 antagonists" block HIV entry into immune cells. However, HIV drug-resistance can occur. Globally, patient access to CCR5 antagonists has been limited because the pre-treatment laboratory test required to determine HIV drug-resistant is expensive and time-consuming. My research will lead to development of computer programs that reliably, rapidly and cheaply determine HIV drug-resistance and thus greatly improve patient access to CCR5 antagonists worldwide.