SynbiCITE 2.0

合成生物学是一个新的和令人兴奋的研究领域，汇集了生物科学家和工程师，旨在开发新的方法来建立和改变生物系统和细胞。生物细胞可以执行由DNA编码的指令驱动的大量活动。这种DNA构成了细胞基因组，基因组作为不同类型细胞的蓝图，由四种互补的化学构建模块组成，称为核苷酸（G，C，A和T），它们以序列连接在一起。DNA的美妙之处在于，这些构建模块可以特异性地配对（G-C和A-T），因此DNA模板可以很容易地复制和复制。DNA中编码的指令被专门翻译成一系列称为蛋白质的大分子，这些蛋白质充当细胞的引擎，执行细胞生存、分裂和生长所需的所有功能，例如将糖等食物来源转化为能量。在过去的20年里，我们“阅读”DNA的能力得到了迅速的提高，以至于今天DNA可以被快速、准确和廉价地阅读。DNA序列是特定细胞的基本指令集，指示其产生特定实体，例如蛋白质。DNA化学合成的进步导致了DNA“书写”能力的提高。合成生物学/工程生物学提供了一个工程框架，允许研究人员设计和编写针对特定应用的合成DNA-这样合成DNA序列可以放置在细胞中执行特定的人类定义的功能。可以应用于一系列应用程序的基础技术称为平台或基础技术。应用领域包括：英国合成生物学工业转化中心（SynbiCITE）为该领域的初创企业和中小企业提供支持，并与一系列跨国公司合作开展项目。SynbiCITE主要通过三种方式提供支持：（a）提供和输送科学和技术专门知识;（B）充当筹资渠道-特别是私营部门筹资渠道;（c）提供商业教育。这些被视为科学基础工业转化的关键组成部分。该战略的实际实施是通过SynbiCITE内的三个活动中心：-生物设计和应用中心-支持设计，并支持和管理概念和开发项目的证明-业务和推广中心-支持和管理投资者联盟和工业俱乐部，以及通过为期四天的MBA和业务增长加速器提供商业教育和培训。Facilities Hub -提供支持公司的设施和专业知识，包括数据分析和学习，设计自动化协议开发以及更一般的项目和公司支持。

Synthetic biology is a new and exciting research field that brings together biological scientists and engineers with the aim of developing new ways to build and alter biological systems and cells. Biological cells can perform a vast array of activities driven by instructions, which are encoded by DNA. This DNA makes up the cells genome, which act as a blueprint for different types of cells and is composed of four complementary chemical building blocks called nucleotides (G, C, A and T) linked together in a sequence. The beauty of DNA is that these building blocks pair up specifically (G-C and A-T) thus the DNA template can be easily copied and replicated. The instructions encoded in DNA are translated specifically into an array of large molecules called proteins which act as the engines of the cell performing all the necessary functions for cells to live divide and grow e.g. the conversion of food sources like sugar into energy. Over the last 20 years advances in our ability to 'read' DNA has rapidly improved so that today DNA can be read rapidly, accurately and inexpensively. The DNA sequences are the basic instruction set for a particular cell to instruct it to produce specific entities, such as proteins. Advances in the chemical synthesis of DNA have resulted in the increasing ability to 'write' DNA. Synthetic Biology/Engineering Biology provides an engineering framework that allows researchers to design and write synthetic DNA tailored to specific applications - such that the synthetic DNA sequences can be placed in cells to perform specific human defined functions. The basic technology, that can be applied across a range of applications, is called platform or foundational technology. Application areas include: health, bioenergy, crops and soil, fine and bulk chemicals, bio remediation, biosensors and biomaterials.UK centre for the industrial translation of synthetic biology (SynbiCITE) are supported start-ups and SMEs in the field, as well as working on projects with a range of multinational companies. SynbiCITEprovides support in three principal ways: (a) by providing and channelling scientific and technical expertise; (b) acting as a conduit for funding - particularly private sector funding; and (c) providing business education. These are seen as key components in the industrial translation of the science base. The practical implementation of the strategy is via three hubs of activity within SynbiCITE: - The BioDesign and Applications Hub - supports design, and supports and manages proof of concept and development projects- The Business and Outreach Hub - supports and manages an Investor Consortium and an industrial club, as well as providing business education and training through a four-day MBA and a business growth accelerator.- The Facilities Hub - provides facilities and expertise in support of companies, including expertise in data analysis and learning, design automation protocol developments and more general projects and company support.