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IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES

IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
裂殖子侵入红细胞受体的鉴定
批准号：
3746485
负责人：
L H MILLER
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3746485
关键词：
Plasmodium Plasmodium falciparum Plasmodium knowlesi biological signal transduction cell cell interaction erythrocytes host organism interaction intracellular parasitism life cycle microorganism immunology protozoal antigen protozoal infection receptor receptor binding surface antigens

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中文摘要
翻译
裂殖子以受体特异性的方式与 红细胞表面，是免疫发挥作用的阶段 封锁入侵。因此，人们对裂殖体表面成分感兴趣。 因为它们在红细胞识别中的作用，以及作为 诱导保护性免疫。我们正在指认P·诺列西， 间日疟原虫和恶性疟原虫对猴子和人的黏附受体 红血球。连接中的组件和之后的信令 裂殖子与红细胞接触的研究也在进行中。
英文摘要
The merozoite interacts in a receptor-specific manner with the erythrocyte surface and is the stage upon which immunity may work to block invasion. Thus, merozoite surface components are of interest because of their role in erythrocyte recognition and as antigens for induction of protective immunity. We are identifying P. knowlesi, P. vivax and P. falciparum receptors for attachment to monkey and human erythrocytes. The components in the junction and the signaling after merozoites make contact with erythrocytes is also under study.
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IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
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