课题基金 / 基金详情

ELECTRON SPIN RESONANCE CENTER

ELECTRON SPIN RESONANCE CENTER
电子自旋共振中心
批准号:
2281573
负责人:
R LINN BELFORD
金额:
$51.75万
依托单位国家:
美国
项目类别:
财政年份:
1985
资助国家:
美国
项目状态:
已结题
起止时间:
1985-09-30 至 1996-03-31

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中文摘要
翻译
伊利诺伊州ESR研究中心成立于1985年10月,是一家 国家生物医学资源,其合作者在103多篇文章中引用了它 在运营的头三年半时间里,出版了各种出版物。这个 IERC的目标是提供区域、国家和 拥有独特而强大的国际生物医学研究共同体 电子自旋领域的实验和理论能力 共振及相关技术。IERC通过以下方式努力实现这一目标 重点放在三个广泛的活动领域:(1)发展-- 扩展实验可能性范围的最先进的仪器 可通过顺磁共振研究获得,(2)开发 新方法论--即更强大的理论和实验 提高精度、灵敏度和适用范围的方法 共振技术,以及(Iii)继续改进IERC作为 为生物医学界提供获得罚款机会的资源 实验设施、专家工作人员咨询、特殊服务(如 作为ESR标准样本项目)和最新信息,包括 中心开发的软件,硬件和仪器的修改, 研讨会、ESR研究和会议新闻(通过ESR中心 通讯)。为实现这些目标,将继续提供支持 要求在未来五年内允许IERC提供五个 研究资源的构成:(1)技术研究和 开发,(2)合作研究,利用特殊设施, IERC的方法和专业知识,与区域、国家和 生物医学及相关科学的国际调查人员,(3) 服务活动;(4)若干培训活动,包括一项新的 招收50名或更多研究生或博士后的计划 个性化培训计划的授权期,以及(5)传播 信息和技术。 IERC将开展的技术研究和开发活动 未来五年的重点是(1)发展和 第一台超高频W波段ESR波谱仪的完善 其版本已投入使用;(2)低频(S频段)ESE, 以及相关的超精细光谱技术;(3)计算 支持电子自旋共振,(4)电子自旋共振成像的发展;和(5) 低频(活体L波段)电子自旋共振波谱的研究进展 仪器和技术。
英文摘要
The Illinois ESR Research Center, established in October of 1985, is a national biomedical resource whose collaborators have cited it in over 103 publications during the first three-and-a-half years of operation. The objective of the IERC is to provide the regional, national, and international biomedical research community with unique and powerful experimental and theoretical capabilities in the area of -Electron Spin Resonance and related techniques. The IERC works towards that objective by focussing on three broad areas of activity: (i) development of state-of- the-art instrumentation to extend the range of experimental possibilities available through paramagnetic resonance investigations, (ii) development of new methodology -- i.e. more powerful theoretical and experimental methods that enhance the precision, sensitivity, and scope of applicability of resonance techniques, and (iii) continual improvement of the IERC as a resource providing the biomedical community with access to fine experimental facilities, expert staff consultation, special services (such as the ESR standard sample project), and up-to-date information, including software developed by the Center, hardware and instrument modifications, workshops, and ESR research and conference news (through the ESR Centers Newsletter). In furtherance of these goals, continuing support is requested for the next five years to allow the IERC to provide the five components of a Research Resource: (1) technological research and development, (2) collaborative research, using the special facilities, methodologies, and expertise of the IERC, with regional, national, and international investigators in the biomedical and related sciences, (3) service activities, (4) several training activities, including a new program to bring in 50 or more graduate or postdoctoral students over the grant period for individualized training programs, and (5) dissemination of information and technology. The technological research and development activities on which IERC will concentrate over the next five-year period are (1) development and perfection of the very-high-frequency W-band ESR spectrometer, the first version of which has become operational; (2) low-frequency (S-band) ESE, and related techniques for hyperfine spectroscopy; (3) computational support for electron spin resonance, (4) ESR imaging developments; and (5) development of low-frequency (L-band in vivo) ESR spectroscopy instrumentation and techniques.
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