FREQUENCY OF HEPATITIS C VIRUS-RNA AND HEPATITIS C VIRUS SEROLOGICAL MARKERS

丙型肝炎病毒(HCV)抗体的存在是先前 和/或持续暴露于丙型肝炎病毒感染。然而，抗体的存在， 在所有情况下，可能都不能准确地表明献血 含有丙型肝炎病毒，具有潜在的传染性。血清和血清中丙型肝炎病毒核糖核酸水平 一般来说，肝脏似乎与疾病活动平行，如以下所示 血清丙氨酸转氨酶(ALT)水平升高。在这项研究中， 用聚合酶链式反应检测丙型肝炎病毒核糖核酸出现的频率和总体一致性 将采用ELISA法和RIBA II法对供者血清进行抗体检测。

The presence of antibodies to hepatitis C virus (HCV) is evidence of prior and/or ongoing exposure to HCV infection. Antibody presence, however, might not, in all cases, accurately indicate whether a blood donation contains HCV and is potentially infectious. Levels of HCV-RNA in serum and liver, in general, appear to parallel disease activity, as indicated by increased serum alanine aminotransferase (ALT) levels. In this study, the frequency and overall concordance of appearance of HCV-RNA, using PCR, and antibody, using ELISA and RIBA II, in donor sera will be undertaken.