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IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES

IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
裂殖子侵入红细胞受体的鉴定
批准号：
3790693
负责人：
L H MILLER
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3790693
关键词：
Plasmodium Plasmodium falciparum Plasmodium knowlesi biological signal transduction cell cell interaction erythrocytes host organism interaction intracellular parasitism microorganism immunology protozoal antigen protozoal infection receptor receptor binding surface antigens

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中文摘要
翻译
裂殖子以受体特异性的方式与红细胞相互作用。 这是一种表面现象，是免疫力可以阻止入侵的阶段。 因此，裂殖体表面成分因其作用而引起人们的兴趣。 在红细胞识别和作为抗原诱导保护性 豁免权。我们正在鉴定诺氏疟原虫、间日疟原虫和恶性疟原虫。 与猴子和人类红细胞结合的受体。这些组件 在接合处和裂殖子接触后的信号 红细胞也在研究中。
英文摘要
The merozoite interacts in a receptor specific manner with the erythrocyte surface and is the stage upon which immunity may work to block invasion. Thus, merozoite surface components are of interest because of their role in erythrocyte recognition and as antigens for induction of protective immunity. We are identifying P. knowlesi, P. vivax and P. falciparum receptors for attachment to monkey and human erythrocytes. The components in the junction and the signaling after merozoites make contact with erythrocytes is also under study.
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IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
IDENTIFICATION OF RECEPTORS FOR MEROZOITE INVASION OF ERYTHROCYTES
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