Cytokine Signalling in Health and Disease

血液系统由不同类型的血细胞（红细胞、白色细胞、血小板等）组成。每种类型细胞的正确数量是由称为细胞因子的化学信使控制的。由于过度活跃的细胞因子信号传导可导致炎症性疾病和白血病，因此它受到体内其他分子的严格控制。该项目旨在确定实现这一目标的确切机制，目的是开发治疗炎症性疾病和白血病的疗法。

The blood system is made up of different types of blood cells (red cells, white cells, platelets etc). The correct number of each type of cell is controlled by chemical messengers called cytokines. Because overactive cytokine signalling can lead to inflammatory disease and leukemia it is tightly controlled by the other molecules in the body. This project aims to determine the exact mechanism whereby this is achieved with the aim of developing therapies to treat inflammatory disease and leukemia.