VAX COMPUTER SYSTEM FOR THE BIOLOGY DEPARTMENT

本申请的长期目标是提供一种用于制造电子设备的方法的状态。 艺术计算设施的教师的研究需要， 生物系，其中许多人是由PHS赠款支持。 朝向 为此，我们建议购置一套新的VAX 3900电脑系统， 以配合部门内一些新的电脑用途。 比如说， 艾伦·邓普顿实验室目前的工作是利用计算机生成基因， 树来寻找遗传标记， 来自生产中使用的各种病原体的细菌菌株 新的重组DNA疫苗。 在这两项研究中， 对于部门内的其他人来说，计算的必要性已经超过了 我们现有的VAX系统的容量。 购买新的VAX计算机 将允许开发和使用DNA序列分析的新程序， 以及维护几个不可替代的数据库。 此外，本发明还提供了一种方法， 使用计算光学切片的教职员工 该部门的设施，需要有一个更快的计算机访问 处理单元以及更大的存储容量， 处理和操纵在奥林巴斯上获得的三维图像 显微镜 因此，购买拟议的VAX计算机及其 附件将有助于几乎所有的研究内进行的 生物系。

The long term objective of this application is to provide a state of the art computing facility for the research needs of members of the faculty of the Biology department, many of whom are supported by PHS grants. Toward this goal, we propose to purchase a new VAX 3900 computer system to accommodate some of the new computing uses in the department. For example, current work in Alan Templeton's laboratory uses computer generated gene trees to search for genetic markers that are genetically characterized bacterial strains from various pathogens which are used in the production of new recombinant DNA vaccines. In both of these studies as well as many others within the department, the necessity for computing has outstripped the capacity of our current VAX system. The purchase of a new VAX computer will allow development and use of new programs for DNA sequence analysis, and for the maintenance of several irreplaceable databases. In addition, members of the faculty who are using the computational optical-sectioning facility of the department, need to have access to a computer with a faster processing unit as well as significantly larger memory capacity in order to process and manipulate three-dimensional images obtained on an Olympus microscope. Thus the purchase of the proposed VAX computer and its accessories would assist nearly all of the research conducted within the department of Biology.