REFLECTANCE-MODE PULSE OXIMETRY

尽管脉搏血氧仪在过去几年中已被广泛使用， 在所有的大医院，脉搏血氧仪的理论基础仍然是 不太了解。 因此，仪器仪表的发展 依赖于经验知识的缓慢获取。 最近， 临床医生表示有兴趣开发一种 在反射模式下操作的经皮血氧计，而不是 在传输模式下。 这种装置可以在地球上的许多地点使用。 身体，并且可以使得能够在电击期间和在电击期间的其他条件下进行监测。 外周血流量受损 我们的努力一直集中在提高理论认识， 脉搏血氧仪 我们已经开发了皮肤的光子扩散模型， 研究组织血容量和其他重要变量对 透射模式和反射模式血氧计的校准。 对组织模型和完整皮肤进行了测量，以确认 模型的有效性。 在模型结果的指导下，我们构造了固态反射率 传感器，可以放置在前额，脸部和胸部， 测量动脉血氧饱和度。

Although pulse oximeters have been used extensively over the last few years in all major hospitals, the theoretical basis of pulse oximetry is still poorly understood. As a result, the development of instrumentation has relied on the slow acquisition of empirical knowledge. Recently, clinicians have expressed interest in the possibility of developing a transcutaneous oximeter that operates in the reflection mode, rather than in the transmission mode. Such a device could be used at many sites on the body, and may enable monitoring during shock and other conditions during which peripheral blood flow is compromised. Our efforts have been focused on improving the theoretical understanding of pulse oximetry. We have developed photon-diffusion models of the skin to study the effect of tissue blood volume and other important variables on the calibration of transmission - and reflection-mode oximeters. Measurements on tissue phantoms and intact skin have been made to confirm the validity of the models. Guided by the model results, we have constructed solid-state reflectance sensors which can be placed on the forehead, face, and chest to obtain measurements of arterial oxygen saturation.