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MRC-University of Glasgow Centre for Virus Research

MRC-University of Glasgow Centre for Virus Research
MRC-格拉斯哥大学病毒研究中心
批准号:
G0801822/1
负责人:
Massimo Palmarini
金额:
$820.52万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2010
资助国家:
英国
项目状态:
已结题
起止时间:
2010 至 --

项目摘要

项目成果

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中文摘要
翻译
申请的目的是建立一个新的国际公认的病毒学研究中心。医学研究委员会?我们在格拉斯哥的高度评价的病毒学部门将重新安置在格拉斯哥大学内的一个新的最先进的建筑里。在Garscube校区的比较医学研究所成立综合病毒学中心(CIV)。这个新组织将汇集一批对当今威胁人类健康的一些最重要的病毒制剂具有多年研究经验的独特专家,以应对21世纪病毒带来的挑战。病毒是种类繁多的病原体,它们作为导致肝炎、艾滋病和癌症等疾病的慢性感染原因,继续对人类健康造成重大负担。病毒还会引起急性、危及生命的感染,如肺炎或脑炎,并对疫苗控制构成挑战,因为它们能够迅速变化,从而在引起严重疾病之前逃避我们免疫系统的检测和破坏。某些病毒从一个物种跳到另一个物种的能力特别令人关切,并构成新的世界流行病的威胁。另一方面,病毒可以作为生物学和医学的工具,因为它们可以丰富我们在细胞水平上对生物学的理解,甚至可以用于提供遗传疾病的治疗和杀死患者的癌细胞。通过整合病毒学的这些方面,并将临床医生和人类病毒专家与专注于动物病毒和病毒流行数学分析的病理学家和科学家结合起来,CIV将为英国提供附加价值和独特的战略资源。疫控中心还将响应为下一代临床医生、兽医和科学家提供更好的培训和职业发展机会的公认需要,这些人将来将负责控制病毒和其他传染原。
英文摘要
The purpose of the application is to build a new internationally recognised centre for research on virology. The Medical Research Council?s highly rated Virology Unit in Glasgow will be re-housed in a new state-of-the-art building within the University of Glasgow?s Institute of Comparative Medicine on the Garscube Campus to form the Centre for Integrated Virology (CIV). This new organisation will address the challenges presented by viruses in the 21st century by bringing together a unique array of experts with many years of research experience on some of the most important viral agents that threaten human health today. Viruses represent a very diverse range of agents that continue to exert a major burden on human health as causes of chronic infection leading to diseases including hepatitis, AIDS and cancer. Viruses also cause acute, life-threatening infections such as pneumonia or encephalitis and present a challenge to control by vaccines due to their ability to change rapidly and hence evade detection and destruction by our immune systems before causing serious disease. The ability of some viruses to jump from one species to another is of particular concern and presents the threat of new world-wide epidemics. On the other hand, viruses can be used as tools in biology and medicine as they can enrich our understanding of biology at the cellular level and can even be used to deliver therapies for genetic diseases and to kill cancer cells in patients. By integrating these aspects of virology and bringing clinicians and human virus experts alongside pathologists and scientists focusing on animal viruses and the mathematical analysis of viral epidemics, the CIV will provide added value and a unique strategic resource for the UK. The CIV will also respond to the acknowledged need for improved training and career development opportunities for the next generation of clinicians, veterinarians and scientists who will in future carry the responsibility for the control of viruses and other infectious agents.
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Virus cross-species transmission. Defining the immunological barriers to viral emergence
  • 批准号:
    MC_UU_00034/3
  • 项目类别:
    Intramural
  • 资助金额:
    $396.53万
  • 财政年份:
    2023
  • 负责人:
    Massimo Palmarini
  • 依托单位:
GeoMx digital spatial profiler: expanding the capabilities of the CVR Virus Genomics and Bioinformatics platform
  • 批准号:
    MR/X01360X/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $38.87万
  • 财政年份:
    2022
  • 负责人:
    Massimo Palmarini
  • 依托单位:
Monkeypox Rapid Research Response
  • 批准号:
    BB/X011607/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $94.25万
  • 财政年份:
    2022
  • 负责人:
    Massimo Palmarini
  • 依托单位:
CVR Reagent Repository
  • 批准号:
    MC_PC_20035
  • 项目类别:
    Intramural
  • 资助金额:
    $25.79万
  • 财政年份:
    2021
  • 负责人:
    Massimo Palmarini
  • 依托单位:
海外基金