TREATMENT OF MALIGNANT BRAIN TUMORS WITH INTERSTITIAL RADIOTHERAPY

尽管采用了多种形式的积极治疗， 高级别胶质瘤，特别是多形性胶质母细胞瘤的存活率较低， 一年多，治愈一般是轶事。 这些肿瘤通常 超出了完全手术切除的范围， 传统的外射束放射治疗受到周围环境的限制， 大脑耐受性 通过将放射性碘125种子直接放入 肿瘤床，我们可以达到高辐射剂量的肿瘤，在一个 对周围正常大脑的辐射急剧下降， 通过在低剂量率下去电离来实现增加的治疗比率。

Despite multi-modality treatment of an aggressive nature, the median survival in high-grade gliomas, especially glioblastoma multiforme is less than a year, and cure is generally anecdotal. These tumors have usually extended beyond the limits of a complete surgical resection and a dose of conventional external beam radiotherapy has been limited by surrounding brain tolerance. By placing radioactive seeds of Iodine 125 directly into the tumor bed, we can achieve a high radiation dose to the tumor, at a sharp fall-off of radiation to the surrounding normal brain, and thereby achieve an increased therapeutic ratio by delevering at low dose rates.