To investigate the performance of scanning laser polarimetry and scanning laser ophthalmoscopy in glaucoma case finding
To investigate the performance of scanning laser polarimetry and scanning laser ophthalmoscopy in glaucoma case finding
批准号:
G1001939/1
负责人:
Michelle Chan
金额:
$28.09万
依托单位国家:
英国
项目类别:
Fellowship
财政年份:
2011
资助国家:
英国
项目状态:
已结题
起止时间:
2011 至 --
中文摘要
青光眼是一种视神经受损,导致视力丧失的眼病。这是世界范围内导致不可逆转失明的最常见原因。它直到晚期才会产生症状,但从早期检查就可以发现异常。然而,目前还没有得到证实的快速测试或组合测试来筛查青光眼。在英国,许多人接受眼压测量,但研究表明,在社区中,大约50%的青光眼仍然没有被发现。扫描激光偏振仪(GDX)和海德堡视网膜断层扫描仪(HRT)是用于诊断和监测青光眼的两种成像设备。分别测量视神经附近神经纤维层的厚度,并用计算机软件分析视神经的轮廓。它们具有快速、客观、可重复性好、可由技术人员操作等优点。本研究旨在评估GDX和HRT作为青光眼筛查工具的联合使用。它将分析诺福克居民的现有数据。许多人接受了眼科检查,以确定他们是否患有青光眼。这些发现的实际应用可能是一种更强大的筛查方法,能够在早期阶段识别出青光眼患者。
英文摘要
Glaucoma is an eye disease in which the optic nerve is damaged, causing loss of vision. It is the commonest cause of irreversible blindness worldwide. It produces no symptoms until advanced, but abnormalities are detectable on examination from an early stage. However, there is no proven rapid test or combination of tests to screen for glaucoma. In the UK, many people undergo eye pressure measurement by an optician, but studies show that round 50% of glaucoma remains undetected in the community. Scanning laser polarimetry (GDx) and Heidelberg Retinal Tomography (HRT) are imaging devices used to diagnose & monitor glaucoma. Respectively, they measure the thickness of the nerve fibre layer near the optic nerve, and analyse the contour of the optic nerve with computer software. They have the advantage of being fast, objective, reproducible and can be carried out by a technician.This research aims to evaluate the combined use of GDx and HRT as screening tools for glaucoma. It will analyse existing data on residents of Norfolk. Many have undergone ophthalmological examination to determine if they have glaucoma or not. The practical application of the findings could be a more robust screening method, being able to identify those with glaucoma at an early stage.
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国内基金
海外基金
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依托单位:
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依托单位:
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负责人:单志广
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依托单位: