Detecting Biomarkers of Brain Health in Dementia

神经细胞之间通过神经突起或神经突起进行交流。神经突起的功能障碍会导致痴呆的临床症状，如认知能力下降。目前，我们不能直接监测活体大脑中神经突起的退化，因此很难确定治疗药物是否具有保护性。我的目标是开发一种血液中的检测系统，使我们能够在疾病进展和治疗干预期间监测这些变化。

Nerve cells communicate with each other through nerve processes or neurites. The dysfunction of neurites results in the clinical symptoms of dementia such as cognitive decline. Currently we cannot directly monitor degeneration of neurites in the living brain and therefore it is difficult to determine whether therapeutic agents are protective. My goal is to develop a detection system in the blood that will allow us to monitor these changes during disease progression and therapeutic intervention.