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KINETICS OF CALCIUM METABOLISM IN CHILDHOOD

KINETICS OF CALCIUM METABOLISM IN CHILDHOOD
儿童期钙代谢动力学
批准号:
4693762
负责人:
J B SIDBURY
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
该研究利用两种不同的钙稳定同位素来确定 钙动力学 由于同位素是非放射性的, 用于儿童和孕妇。 给出了一种同位素 静脉注射另一种口服 因为同位素的性质不同 原子量,这两种钙可以在质谱仪中测定 同步 仅需12小时采血。 尿液 每8小时连续收集一次,持续2周。 使用 由Mones Berman博士设计的建模程序,可以确定大小 几个钙池中。 对研究进行了修订,以纳入妊娠期和哺乳期研究 妇女 我们的研究对象是在妊娠晚期, 在哺乳期结束后6个月重复研究。 结束了。 普拉德-威利综合征继续与遗传成分有关, 在改变代谢和未来的钙平衡研究中有明显的证据。
英文摘要
The study utilizes two different stable isotopes of calcium to determine calcium kinetics. The fact that the isotopes are non-radioactive, they can be used in children and pregnant women. One isotope is given intravenously, the other by mouth. Since the isotopes have different atomic weights, the two calciums can be determined in the mass spectrometer simultaneously. Blood sampling is required for 12 hours only. Urine collections are made continuously every 8 hours for 2 weeks. Using the modeling program designed by Dr. Mones Berman, one can determine the size of the several calcium pools. The study had been amended to include the study of pregnant and lactating women. Our subject has been studied in the third trimester, during lactation and the study will be repeated 6 months after lactation has concluded. The Prader-Willi Syndrome continues in relation to the genetic components, evidense for altered metabolism and in the future calcium balance studies.
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会议论文
GLYCOGEN STORAGE DISEASE
EVALUATION OF NALMEFENE, AN ENDORPHIN ANTAGONIST, IN THE CONTROL OF APPETITE
GLYCOGEN STORAGE DISEASE
METABOLISM IN CHILDREN WITH GLYCOGEN STORAGE DISEASE, TYPE I
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