INVOLVEMENT OF CALCIUM, FODRIN, AND GLUTAMATE IN SEIZURES

这项工作将涉及癫痫病灶的研究和 谷氨酸受体的状态，细胞骨架蛋白fodrin和通量 钙离子。 癫痫发作已被证明是作为一种 这是外部钙离子向细胞内部转移的结果。 由于钙离子也被称为激活钙蛋白酶， fodrin，负责维护 膜的 这项研究的兴趣问题是确定是否 胞衬蛋白的分解与癫痫活动的扩散直接相关。

The work will involve the study of epileptic foci and the evaluation of the status of glutamate receptors, the cytoskeletal protein fodrin and the flux of calcium ions. The epileptic seizure has been demonstrated to occur as a result of a shift of external calcium ions to the interior of the cell. Since calcium ions are also known to activate calpain, which degrades fodrin, which is responsible for maintaining the integrity of the membrane. The question of interest in this study is to determine whether fodrin breakdown is directly linked to the spread of epileptic activity.