Programme 1: Musculoskeletal health in later life

该方案的目的是减轻慢性非传染性肌肉骨骼疾病的负担，如骨质疏松症、骨关节炎和肌肉减少症（分别是世界上最常见的骨骼、关节和肌肉疾病）。我们的方法整合了观察流行病学和机械理解，以开发旨在优化肌肉骨骼健康的晚年新型干预措施。我们的工作已经为世卫组织和法语国家国际组织制定的战略提供了信息。通过对潜在机制的调查，我们正在评估可能在老年人中广泛提供的干预措施，以成功实施潜在的新公共卫生战略，减少这些疾病造成的健康负担。

The aim of this programme is to reduce the burden of chronic non-communicable musculoskeletal disorders such as osteoporosis, osteoarthritis and sarcopenia (the commonest disorders worldwide of bone, joint and muscle respectively). Our approach integrates observational epidemiology and mechanistic understanding to develop novel interventions in later life aimed at optimising musculoskeletal health. Our work has already informed strategies developed by the WHO and IOF. Complemented by investigation of underlying mechanisms, we are evaluating interventions that might be widely delivered in older age, in order to successfully implement potential novel public health strategies which will reduce the health burden resulting from these disorders.