Establishment of a National Network on Musculoskeletal Ageing

我们的总体目标是建立一个新的国家网络，它将支持肌肉骨骼老化研究能力和战略的阶段性变化，方法是确定：关键的可处理的研究优先事项；开发一个综合的多学科小组以解决已确定的研究差距；提供一个传播最佳实践的平台；支持早期职业研究人员(ECR)建设研究能力，并确保现有UKRI投资的寿命；以及协调持续的创新研究计划，以确定、开发和将我们的发现科学成果转化为临床影响。至关重要的是，该网络将通过确定保持老年流动性的方法，为实现政府到2035年多生活5年的“大挑战”目标做出贡献。该网络将汇集三位主要申请者在科学上的卓越之处。专注于骨、肌肉和关节的主要慢性非传染性疾病(骨质疏松症、骨质疏松症、类风湿性关节炎和骨关节炎)，这些群体的整合将激发真正的从板凳到床边的方法，为卫生政策提供强有力的证据基础，为英国肌肉骨骼老化研究能力/能力的阶段性变化奠定基础，并促进健康跨度的增加。

Our overall aim is to establish a new national network which will underpin a step change in musculoskeletal ageing research capacity and strategy, by identifying: key tractable research priorities; developing an integrated multi-disciplinary grouping to address the identified research gaps; providing a platform to disseminate best practice; supporting Early Career Researchers (ECRs) to build research capacity and ensure longevity to current UKRI investments; and coordinating an ongoing programme of innovative studies to identify, develop and translate findings from our discovery science to clinical impact. Crucially the network will contribute to delivering the government “Grand Challenge” target of 5 more years of independent living by 2035, by identifying approaches to maintain mobility in old age. The network will bring together the scientific excellence of the three principal applicants. Focusing on the leading chronic non-communicable disorders of bone, muscle and joint (osteoporosis, sarcopenia, rheumatoid arthritis and osteoarthritis), the integration of these groups will galvanize a truly bench to bedside approach to provide a strong evidence base for health policy, underpinning a step change in UK musculoskeletal ageing research capability/capacity, and promoting increased healthspan.