ISARIC Clinical Characterisation Protocol UK (CCP-UK) - a companion study for patients with Cancer and COVID-19 (CCP-CANCER-UK)

2019年，一种名为SARS-CoV-2的新病毒出现，它会导致一种名为新冠肺炎的疾病。这通常是轻微的，但也可能是严重的，导致病毒性肺炎；预计每100名感染者中就有一人死于此病。然而，癌症患者感染和死亡的风险可能更高，因为他们的治疗或癌症导致免疫系统减弱。我们将解决癌症患者需要解决的许多紧急问题，以帮助确保早期诊断，确保S给出正确的屏蔽建议，并使医生和患者能够在疫情期间做出明智的治疗决定。这将通过收集超过5,000名癌症患者的详细数据来实现，该研究招募到主要的英国研究，该研究描述了新冠肺炎(CCP-UK研究)。当癌症数据与丰富的新冠肺炎数据联系在一起时，将使以下重要问题得到解答：癌症患者死于新冠肺炎的比例是多少？根据癌症类型和癌症治疗的不同，这一比例有何不同？癌症患者使用新冠肺炎会出现哪些症状？这会因癌症的类型和治疗方法的不同而有所不同吗？什么样的癌症治疗会使人们患重病和死亡的风险更高？癌症患者需要什么样的医疗资源(包括重症监护)来治疗新冠肺炎？考虑到年龄和其他疾病，癌症患者和非癌症患者的预后如何？

2019 a new virus called SARS-CoV-2 emerged, which causes a disease termed COVID-19. This is often mild but can also be severe, leading to viral pneumonia; about one in 100 infected people are expected to die of i t. However, cancer patients are likely to be at higher risk of infection and death as they have a weakened immune system as a result of either their treatment or their cancer. We will tackle many urgent questions that need answering in cancer patients to help ensure early diagnosis, that the correct shielding advice i s given, and to enable doctors and patients to make informed decisions regarding treatment during the pandemic. This will be achieved by collecting detailed data from the over 5,000 cancer patients recruited into the main UK study which has described COVID-19 (CCP-UK study). The cancer data when linked with the rich COVID-19 data will enable the following important questions to be answered:What proportion of cancer patients die from COVID-19? How does this vary based on cancer type and cancer treatment?What are the symptoms cancer patients develop with COVID-19? Does this vary based on type of cancer and treatment?What type of cancer treatments puts people at higher risk of severe illness and death?What kind of healthcare resources are needed (including intensive care) to treat COVID-19 in cancer patients?How do the outcome of patients with cancer compare with non-cancer patients taking into account age and other illnesses?