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GROWTH RETARDATION--HPA AXIS RESPONSE TO CRH AND CORTISOL CHALLENGES

GROWTH RETARDATION--HPA AXIS RESPONSE TO CRH AND CORTISOL CHALLENGES
生长迟缓——HPA 轴对 CRH 和皮质醇挑战的反应
批准号：
6297120
负责人：
Delia M Vazquez
金额：
$0.02万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6297120
关键词：
child (0-11) clinical research corticotropin releasing factor cortisol hormone regulation /control mechanism human subject hypothalamic pituitary adrenal axis pituitary dwarfism postnatal growth disorder psychological stressor somatotropin stress

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中文摘要
翻译
本研究旨在研究矮小儿童和心理矮子的生长激素（GH）和下丘脑-垂体-肾上腺（HPA）轴生理。目的是解决以下可能性：在发育过程中反复的心理压力激活下丘脑轴；导致其元素的异常调节，这最终有利于对生长激素释放的强直性抑制和生长失败。
英文摘要
This proposal studies the growth hormone (GH) and hypothalamic pituitary adrenal (HPA) axis physiology in children with short stature and psychosocial dwarfs. The aim is to address the possibility that: repeated psychological stress during development activates the HPA axis; leads to an abnormal regulation of its elements and this ultimately is conducive to a tonic inhibition on GH release and growth failure.
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ALTERING NEUROPLASTICITY DURING DEVELOPMENT
DEPRESSION RISK, INFANT-MOTHER ATTACHMENT AND CORTISOL
DEPRESSION RISK, INFANT-MOTHER ATTACHMENT AND CORTISOL
DEPRESSION RISK, INFANT-MOTHER ATTACHMENT AND CORTISOL
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