ANALYSIS OF MECHANICAL FORCES ON BRAIN UNDERSTANDING TRANSTENTORIAL HERNIATION

在过去的一年里，我们在所有三个方面都取得了进展 重大研究项目。正如我们在以前提交的材料中指出的，其中一个 这些研究涉及对基因转录调控的研究。 编码Na+，K+-ATPase的a-链异构体。这个项目 涉及对促进剂、增强剂、消音剂和同源物的研究 结合蛋白。相当大的核苷酸序列搜索，载体 以及寡核苷酸设计和其他GCG程序的使用是必需的。

During the past year, we have made progress in all three of our major research projects. As noted in our previous submissions, one of these involves the study of the transcriptional regulation of genes encoding the a-chain isoforms of the Na+, K+--ATPase. This project involves studies of promoters, enhancers, silencers, and cognate binding proteins. Considerable nucleotide sequence searching, vector and oligonucleotide design, and other GCG program use are required.