PEDIATRIC NEPHROLOGY TRAINING

儿科肾脏病学培训计划的目的是 德克萨斯大学西南医学中心将培训儿科医生 作为学术儿科肾病学的独立研究者的职业生涯。 在美国，儿科肾病学家短缺， 儿科肾病学每年都有很多职位空缺。最 儿科肾病学的学员没有接受过准备培训 独立研究的职业。该申请要求资金用于两个 每年的儿科肾病研究员职位（临床培训是 由儿科部支付）。 研究员将花费至少两个 在实验室工作多年，兴趣包括：1）肾脏发育 生理学; 2）信号转导; 3）近端小管NaCl的调节 转运; 4）肾小管酸中毒的发病机制; 5）柠檬酸盐转运 近曲小管酸化的分子机制 7）缺血对肾移植的影响 排斥反应和巨噬细胞活化的机制; 8）热的作用 休克蛋白在急性肾功能衰竭中的作用; 9）高血压的发病机制。 此外，研究员还参加新闻部每周举行的会议。 儿科学旨在为学术医学的职业生涯做准备。 内容包括统计学、计算机在生物医学中的应用 研究，如何写手稿和赠款，以及使用动物和 人类在研究医学和生物医学伦理学相关主题 研究在这些讲座中得到了大力强调， 该大学还为研究员举办伦理讲座。联合周刊 儿科和内科肾脏学会议 包括临床和分子生物学杂志俱乐部，肾脏大查房， 肾脏研究会议和肾脏生理学系列讲座。家伙 还参加基础科学部门的研讨会。学员们密切 由他们的研究导师和私家侦探监督以确保 该培训计划的目标已经实现。

The purpose of the training program in Pediatric Nephrology at the University of Texas Southwestern Medical Center is to train pediatricians for careers as independent investigators in academic Pediatric Nephrology. There is a shortage of Pediatric Nephrologists in the United States and many positions in Pediatric Nephrology go unfilled each year. Most trainees in Pediatric Nephrology do not receive training to prepare them for independent research careers. This application requests funds for two Pediatric Nephrology fellowship positions per year (clinical training is paid by the Department of Pediatrics). Fellows will spend at least two years in laboratories whose interests include: 1)renal developmental physiology; 2) signal transduction; 3) regulation of proximal tubule NaCl transport; 4) pathogenesis of renal tubular acidosis; 5) citrate transport and metabolism; 6) molecular mechanisms of proximal tubule acidification and phosphate transport; 7) the effect of ischemia in renal transplant rejection and the mechanism for macrophage activation; 8) role of heat shock proteins in acute renal failure; 9) pathogenesis of hypertension. In addition, fellows attend weekly conferences given by the Department of Pediatrics designed to prepare fellows for careers in academic medicine. Topics covered include statistics, use of Computers in biomedical research, how to write a manuscript and grant, and use of animals and humans in research. Topics related to ethics in medicine and biomedical research are strongly emphasized in these lectures and additional medical ethics lectures are also given by the University for fellows. Joint weekly conferences by the Divisions of Pediatric and Internal Medicine Nephrology include clinical and molecular biology journal clubs, renal grand rounds, renal research conference, and a renal physiology lecture series. Fellows also attend seminars in basic science departments. Trainees are closely supervised by their research mentor as well as the P.I. to insure that the goals of this training program are achieved.