METABOLIC CONSEQUENCES OF ENZYME ENZYME INTERACTIONS

培训和传播方面的一项重大努力 BRTP GRANT是我们一年一度的核磁共振研讨会。今年的研讨会是 题为“新陈代谢研究专题讨论会和培训VI：13C” 1998年5月7日在德克萨斯大学西南分校举行。该计划的目标是 正在使用或考虑使用或考虑使用13C核磁共振或 用于代谢研究的13C质谱学。晨练 会议介绍了~(13)C核磁共振同分异构体分析， 实验设计和解释，~(13)C核磁共振波谱分析， 和一个非正式的时间，在这个时间里，研讨会的与会者可以 展示并讨论他们的数据。在下午的会议上，嘉宾 教授专注于代谢中的13C核磁共振和13C质谱学 侧重于动力学分析的研究。接待处和 晚宴为与会者提供了一个互动的时间 扬声器。晚餐后，罗伯特·舒尔曼博士讨论了他的实验室最近 人类大脑的新陈代谢研究。演讲者名单如下 在《研究进展摘要》中提供。介绍手册说明 研讨会被发送给潜在的与会者和一个研讨会 手册包含在附录材料中。研讨会的主题是 有70多人参加，与会者主要来自德克萨斯州， 但有几个人来自佛罗里达州、佐治亚州、马萨诸塞州、密苏里州和 田纳西州。向与会者提供研讨会讲义副本一份 包括在附录中。获得对研讨会的支持 来自注册费、企业赞助商和 放射学。收到的支持包括在其他基金中 “资源摘要”页。这种支持涵盖了晚宴和招待会。 BRTP资金用于本组织的工作人员支助 研讨会并支持我们的外部成员的差旅费用 咨询委员会。(培训2)报告期：(09/01/97-08/31/98)

A major effort of the training and dissemination aspects of the BRTP grant is our annual NMR symposium. This year's symposium was titled "Symposium and Training VI: 13C in Metabolic Research" and was held at UT Southwestern on May 7, 1998. The program was aimed at faculty, fellows, and students who are using or considering 13C NMR or 13C mass spectrometry for metabolic studies. The morning training session was an introduction to 13C NMR isotopomer analysis, factors in experimental design and interpretation, analysis of 13C NMR spectra, and an informal time in which symposium attendees could briefly present and discuss their data. In the afternoon session, the guest faculty focused on 13C NMR and 13C Mass Spectrometry in metabolic research with an emphasis on analysis of kinetics. The reception and dinner provided a time for interaction between the attendees and speakers. After dinner, Dr. Robert Shulman discussed his lab's recent metabolic studies in the human brain. A list of the speakers is provided in the Summary of Research Progress. Brochures describing the symposium were sent to potential attendees and a symposium brochure is included in the appendix materials. The Symposium was attended by more than 70 people, with attendees primarily from Texas, but several coming from Florida, Georgia, Massachusetts, Missouri, and Tennessee. A copy of the Symposium handout supplied to the attendees is included in the Appendix. Support for the Symposium is obtained from registration fees, corporate sponsors, and the Department of Radiology. The support received is included in OTHER FUNDS on the Resource Summary page. This support covered the dinner and reception. BRTP funds were used for staff support in the organization of the Symposium and to support the travel costs of members of our External Advisory Committee. (Training 2) REPORT PERIOD: (09/01/97-08/31/98)