A multicentre randomised controlled trial of probiotic and peanut oral immunotherapy for the treatment of peanut allergy

为了防止死亡和改善管理，需要对食物过敏进行根治性治疗。我们最近试验了一种治疗花生过敏的新疗法，效果非常好。接受益生菌和花生口服免疫疗法（PPOIT）治疗的儿童中，超过80%的儿童耐受花生，而接受安慰剂治疗的儿童中，这一比例为4%。我们现在计划进行更大规模的多中心试验来证实这些发现。如果成功，我们将建立一种治疗花生过敏甚至所有食物过敏的新方法。

A curative treatment for food allergy is required to prevent deaths and improve management. We recently trialed a new treatment for peanut allergy that was highly effective. Over 80% of children treated with Probiotic and Peanut Oral ImmunoTherapy (PPOIT) tolerated peanut as compared to 4% of children who received placebo. We now plan a larger multicentre trial to confirm these findings. If successful, we will have established a new treatment for peanut allergy and possibly all food allergies.