CORE--ASSESSMENT, CO-MORBIDITY, AND HEALTH SERVICES RESEARCH

评估、合并症和卫生服务研究的核心将 支持以下方面的干预项目和试点研究 领域：1)招募和筛选符合条件的患者 参与研究；2)保留参与研究的对象 研究；3)评估受试者是否存在合并症 可能影响遵守和响应的条件 干预措施；4)参与研究的受试者的功能评估 干预研究，包括使用自我报告措施和 基于性能的物理容量测量；以及5)成本分析- 干预措施的有效性和成本效用。 为实现这些目标，核心有以下具体目标：1) 建立诊断为间歇性心绞痛的患者登记表 跛行和充血性心力衰竭；2)制定和实施 全面的评估方案，包括人口统计、临床、 在IS、入侵检测和入侵检测中使用的心理社会和功能状态测量 所有试点研究；3)收集医疗保健消费数据 资源，包括治疗和治疗的直接和间接费用 使用的医疗服务的总成本、自付成本和第三方成本， IS、入侵检测系统和试点研究所有治疗部门的受试者；5) 收集与不同人群相关的生活质量结果的数据 6)进行成本效益和成本-- 使用公认的方法对干预措施进行效用分析。 评估、合并症和卫生服务研究核心也将 提供机会，以提高研究技能的发展 初级调查人员，包括博士后研究员和初级教员， 和通过研究开发核心确定的研究伙伴， 包括为相关主题的试点研究项目提供支持 对伊斯兰会议组织的活动的支持。因此，核心将成为不可或缺的一部分。 通过Patient构建马里兰大学的OAIC 关于合并症以及功能和健康的数据收集 状况、进行成本效益分析和教育 临床流行病学和卫生服务领域的调查人员 研究。

The Assessment, Comorbidity and Health Services Research Core will support the intervention projects and pilot studies in the following areas: 1) recruitment and screening of patients eligible for participation in the studies; 2) retention of subjects participating in the studies; 3) assessment of subjects for the presence of comorbid conditions which might influence both compliance with and response to the interventions; 4) functional assessment of subjects participating in the intervention studies including use of self-report measures and performance-based measures of physical capacity; and 5) analysis of cost- effectiveness and cost-utility of the interventions. To accomplish these goals, the Core has the following specific aims: 1) To develop registries of patients with the diagnoses of intermittent claudication and congestive heart failure; 2) To develop and implement a comprehensive assessment protocol including demographic, clinical, psychosocial, and functional status measures for use in the IS, IDS, and all pilot studies; 3) To collect data on the consumption of health care resources, including both direct and indirect costs of treatment and total, out-of-pocket, and third-party costs of health services utilized, by subjects in all treatment arms of the IS, IDS, and pilot studies; 5) To collect data on quality of life outcomes associated with the different arms of the interventions; and 6) To conduct cost-effectiveness and cost- utility analyses of the interventions, using accepted methodology. The Assessment, Comorbidity and Health Services Research Core will also provide opportunities to enhance the development of research skills of junior investigators, including postdoctoral fellows and junior faculty, and research associates identified through the Research Development Core, including providing support for Pilot Research Projects on topics related to the activities of the OAIC. Thus, the Core will be an integral part of the University of Maryland OAIC through the construction of patient registries, collection of data on comorbidities and functional and health status, conduct of cost-effectiveness analyses, and education of investigators in the areas of clinical epidemiology and health services research.