课题基金 / 基金详情

PSYCHOIMMUNOLOGICAL&NEUROENDOCRINOLOGICAL RESPONSE OF CHRONIC FATIGUE

PSYCHOIMMUNOLOGICAL&NEUROENDOCRINOLOGICAL RESPONSE OF CHRONIC FATIGUE
心理免疫学
批准号:
6264889
负责人:
KEH M LIN
金额:
$0.1万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30

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项目成果

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中文摘要
翻译
利用临床、神经内分泌学和心理免疫学领域的最新研究方法,对一组慢性疲劳综合征或神经衰弱患者进行研究。 假设这些患者的一个亚组将表现出特征性免疫学异常,包括T淋巴细胞功能障碍、NK细胞细胞毒性降低和细胞因子浓度升高。 神经内分泌变化包括血浆皮质醇和ACTH浓度降低。还将检查这些结果的跨种族可比性。
英文摘要
To utilize state of the art methodologies derived from clinical, neuroendocrinol ogical and psychoimmunological fields to study a group of patients with chronic fatigue syndrome or neurasthenia. It is hypothesized that a subset of these patients will manifest characteristic immunological abnormalities including T lymphocyte dysfunction, decreased NK cell cytotoxicity, and increased cytokine concentrations. Neuroendocrine changes will include reduced plasma cortisol and ACTH concentrations. Cross ethnic comparability of these findings will also be examined.
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会议论文
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Ethnic Variations in Antidepressant Response
INFLUENCE OF ETHNICITY ON BRAIN LITHIUM--LITHIUM MRS
DETERMINANTS OF CYTOCHROME P450 ACTIVITY IN HUMANS
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