课题基金 / 基金详情

ROLE OF THE KIDNEY IN GLUCOSE HOMEOSTASIS IN NORMAL AND DIABETIC HUMANS

ROLE OF THE KIDNEY IN GLUCOSE HOMEOSTASIS IN NORMAL AND DIABETIC HUMANS
肾脏在正常人和糖尿病人葡萄糖稳态中的作用
批准号:
6113725
负责人:
JOHN E GERICH
金额:
$1.48万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30

项目摘要

项目成果

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中文摘要
翻译
检验2型糖尿病患者肾脏葡萄糖生成过多的假设,并检验胰岛素抑制正常人RGP以及这种抑制在NIDDM中受损的假设。为了验证这一假设,即人的肾脏有助于在低血糖期间代偿性增加血浆中葡萄糖的出现,这在NIDDM中是不可避免的;是餐后葡萄糖摄取和乳酸和丙氨酸释放的重要部位......
英文摘要
To test the hypothesis that there is excessive renal glucose production in people with type 2 diabetes mellitus and to test the hypothesis that insulin suppresses RGP in normal humans and that this suppression is impaired in NIDDM. To test the hypothesis that the human kidney contributes to the to the compensatory increase in appearance of glucose in plasma during hypoglycmia and this is impared in NIDDM; is an important site of postprandial uptake of glucose and release of lactate and alanine ......
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MECHANISM FOR IMPAIRED GLUCAGON RESPONSE TO HYPOGLYCEMIA IN DM
  • 批准号:
    7200078
  • 项目类别:
  • 资助金额:
    $0.03万
  • 财政年份:
    2005
  • 负责人:
    JOHN E GERICH
  • 依托单位:
HORMONAL AND SUBSTRATE REGULATION OF RENAL AND HEPATIC GLUCONEOGENESIS
  • 批准号:
    7200129
  • 项目类别:
  • 资助金额:
    $0.29万
  • 财政年份:
    2005
  • 负责人:
    JOHN E GERICH
  • 依托单位:
Comparison of the Effects of Glyburide and Glimpiride
  • 批准号:
    7040051
  • 项目类别:
  • 资助金额:
    $8.54万
  • 财政年份:
    2004
  • 负责人:
    JOHN E GERICH
  • 依托单位:
Mechanism for Impaired Glucagon Response to Hypoglycemia in DM
  • 批准号:
    7040023
  • 项目类别:
  • 资助金额:
    $0.05万
  • 财政年份:
    2004
  • 负责人:
    JOHN E GERICH
  • 依托单位:
海外基金