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HIV VACCINE PREPAREDNESS STUDY AND EFFICACY TRIAL

HIV VACCINE PREPAREDNESS STUDY AND EFFICACY TRIAL
HIV 疫苗准备研究和功效试验
批准号：
6115740
负责人：
MICHAEL MARMOR
金额：
$2.1万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6115740
关键词：
AIDS vaccines HIV infections clinical research clinical trials epidemiology genetic polymorphism health behavior human immunodeficiency virus human subject

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中文摘要
翻译
本提案是关于HIV疫苗准备研究的，目的如下：1）评估在纽约市进行疫苗有效性试验的可行性。 2)确定HIV的血清发病率及其与行为和生物学辅助因子的关系; 3）验证风险评估量表，以测量与HIV传播相关的风险行为; 4）评估研究人群中HIV的抗原和遗传变异性; 5）为随后的遗传和免疫学分析提供标本。DNA分离、寡核苷酸扩增、PCR、重组DNA技术、RNA分离、血液分离和层流罩的使用。
英文摘要
This proposal is for HIV Vaccine Preparedness studies with the following aims: 1) assess the feasibility of a vaccine efficacy trial in NYC. 2) to determine the seroincidence of HIV and its association with behavioral and biological cofactors; 3) to validate risk assessment scales to measure risk behavior associated with HIV transmission: 4) to evaluate the antigenic and genetic variability of HIV in the study population; 5) to contribute specimens for subsequent genetic and immunologic analysis.The lab was used for the following: DNA isolation, oligonucleotide synthsis, PCR, recombinant DNA techniques, RNA isolation, blood separation and use of laminar flow hoods.
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