Dissecting the central organisation of cough neural networks

咳嗽是肺部疾病最普遍的症状，也是人们寻求医疗建议的最常见原因。然而，咳嗽神经过程定义不清，因此目前的咳嗽治疗在很大程度上无效，使咳嗽成为一个重大的未满足的临床问题。该项目将采用新的病毒策略来解剖和操纵大脑中的咳嗽神经通路，为气道感觉和咳嗽的神经处理提供见解。

Cough is the most prevalent symptom of lung disease and the most common reason for people to seek medical advice. However, cough neural processes are poorly defined and as a result current cough therapies are largely ineffective making cough a significant unmet clinical problem. This project will novel viral strategies to dissect and manipulate cough neural pathways in the brain, providing insights into the neural processing of airway sensations and coughing.