DOES FSH SECRETE MORE IRREGULARLY THAN LH

最近引入的近似熵统计（ApEn） 显示LH和FSH的分泌特征存在显著差异 在绵羊中，以及基于对5名受试者的初步研究，在FSH女性中 似乎比LH更不规则地分泌。 这 美国国立卫生研究院的小企业创新研究基金将延长 通过提供资金，研究妇女状况的变化， LH和FSH在另外5名女性中。 这涉及到获取样本 血液的每7.5分钟，24小时，从五名妇女在第2-5天的 卵泡阶段的周期，并再次，一个月后，没有 从黄体中期取样。 这项研究将提供一个远 更好的信息基线，可作为未来的参考 比较分泌相对规律性差异的研究 这些促性腺激素在其他生命阶段的妇女或与其他 病症，例如绝经期、绝经后、多囊 卵巢综合征，伴有短黄体期缺陷，并伴有其他 生殖状态。 ApEn统计提供了完全不同的 信息补充了通过常规技术获得的信息， 脉搏分析

The recently introduced approximate entropy statistic (ApEn) has revealed striking differences in the profiles of secretion of LH and FSH in sheep and, based on a pilot study of five subjects, in women with FSH appearing to be secreted in a far more irregular fashion than LH. This Small Business Innovative Research grant from the NIH will extend the pilot study in women by providing funding to study changing profiles of LH and FSH in an additional five women. This involves obtaining samples of blood every 7.5 min for 24 hrs from five women during days 2-5 of the follicular phase of their cycle and again, after a month with no sampling, from the mid-luteal phase. The study will provide a far better baseline of information that can serve as a reference for future studies comparing differences in relative regularity of the secretion of these gonadotropins in women in other stages of life or with other conditions, e.g. perimenopausal, post-menopausal, with polycystic ovarian syndrome, with short luteal phase defect, and with other reproductive states. The ApEn statistic provides completely different information complementing that obtained by conventional techniques of pulse analysis.