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PROTEIN METABOLISM AND ENERGY EXPENDITURE IN CUSHING'S SYNDROME

PROTEIN METABOLISM AND ENERGY EXPENDITURE IN CUSHING'S SYNDROME
库欣综合征中的蛋白质代谢和能量消耗
批准号：
6275256
负责人：
DAVID J BRILLON
金额：
$5.51万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6275256
关键词：
Cushing's syndrome bioenergetics calorimetry clinical research human data hypercortisolism postoperative state preoperative state protein metabolism stable isotope

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中文摘要
翻译
慢性高皮质醇血症对底物代谢和能量的影响 支出(EE)还没有得到很好的阐明。该协议将 库欣综合征患者底物动力学和EE测定 治疗性手术前后均使用稳定示踪剂 同位素和间接量热法测量。此协议仅用于 今年的CDMAS。Brillon博士参加了数据管理实践课程 这将帮助他对收集的关于受试者的数据进行最终分析 在这一分项目中看到了前几年的情况。
英文摘要
The effect of chronic hypercortisolemia on substrate metabolism and energy expenditure (EE) has not been well elucidated. This protocol will determine substrate kinetics and EE in patients with Cushing's Syndrome both before and after therapeutic surgery, utilizing stable tracer isotopes and indirect calimetry measurements. This protocol used only CDMAS this year. Dr. Brillon took the Data Management Practicum class that will help him do the final analyses of his data collected on subjects seen in prior years in this subproject.
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