INFANT HEME CATABOLISM AND CARBON MONOXIDE DETECTION

我们继续发展一氧化碳(CO)监测 溶血的实验室和床边诊断技术 其他原因导致的总胆红素产量增加。这涉及到 开发和改进仪器和技术，用于 一氧化碳排泄量的测定。这些努力，与Natus合作 加利福尼亚州圣卡洛斯的Medical，Inc.已经生产了一种 便携式非侵入性床旁监护仪 潮气呼气CO作为各种原因下胆红素生成的指标。我们 用CO评估了这台仪器，以前被称为婴儿呼吸 1996年与新生儿测量的有效率为96%。最近， 仪器更名为CO-Stat，已在人群中进行了评估 从新生儿到成年人的年龄。

We continue our development of carbon monoxide (CO)-monitoring technology for laboratory and bedside diagnosis of hemolysis or increased total bilirubin production from other causes. This involves developing and refining instrumentation and techniques for the measurement of excreted CO. These efforts, in cooperation with Natus Medical, Inc. of San Carlos, CA, have resulted in the production of a portable, non-invasive instrument for the bedside monitoring of end- tidal breath CO as an index of bilirubin production for all causes. We evaluated this instrument, formerly known as Baby's Breath, with a CO measuring efficacy of 96%, with neonates in 1996. Recently, the instrument renamed CO-Stat, has been evaluated in a population ranging in age from neonates to adults.