课题基金 / 基金详情

RELATIONSHIP OF AGE TO CIRCADIAN DESYNCHRONY IN PERMANENT NIGHT SHIFT WORK

RELATIONSHIP OF AGE TO CIRCADIAN DESYNCHRONY IN PERMANENT NIGHT SHIFT WORK
长期夜班工作中年龄与昼夜节律不同步的关系
批准号：
6278133
负责人：
ROBERT L SACK
金额：
$2.86万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6278133
关键词：
aging behavioral /social science research tag circadian rhythms clinical research environmental adaptation hormone therapy human subject human therapy evaluation melatonin occupations psychophysiology sleep

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中文摘要
翻译
总体目标是了解减少的生理基础 对长期夜班工作的容忍，这通常与 老龄化，并试图改善对长期夜间工作的适应 褪黑激素管理。适时服用褪黑素 将作为一种提高夜班工作适应能力的方法进行测试 纠正睡眠和基础睡眠之间的任何相角干扰 昼夜节律。
英文摘要
The overall goal is to understand the physiological basis for the reduced tolerance to permanent night shift work that is commonly associated with aging, and to attempt to improve adaptation to permanent night work with melatonin administration. Appropriately-timed melatonin administration will be tested as a method to improve adaptation to night shift work by correcting any phase angle disturbance between sleep and underlying circadian rhythms.
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