STRUCTURE OF SUP35 FIBERS

朊病毒有一种新的遗传类型，它改变了表型 我是基于蛋白质的遗传， 构象状态，而不是改变核酸的遗传 acids. 来自酵母的Sup 35蛋白通常参与 翻译终止 然而，在某些条件下， 像朊病毒一样形成长纤维 Ile STEM用于确定 不同形式纤维及其中间体的质量/长度 列队

Prions have a new type of inheritance mi which altered phenotypes am based on the inheritance of proteins with self-perpetuating altered conformational states, rather than the inheritance of altered nucleic acids. The Sup35 protein from yeast is normally involved in translation termination. However, under certain conditions it behaves like a prion and forms long fibers. Ile STEM was used to determine the mass/length of different forms of fibers and their intermediates in formation.