Continuous Measurement of Breathlessness

描述(申请人提供)：呼吸系统疾病患者 上气不接下气的症状(呼吸困难)是寻找 医疗救治。目前测量呼吸困难的方法有患者 在递增的运动测试中提供每分钟的评分。是这样的 “离散”方法有其局限性：1)当患者通过 话筒，他们必须指向刻度上的数字，这可能会导致录音 错误；2)在严重损伤的患者中，只有少数几个评级 气喘吁吁；3)关于进行者的信息丢失 上气不接下气的本质，因为患者被随意要求评级 而不是气喘吁吁的实际变化的时间段。这个 该项目的长期目标是开发一种持续的方法来 测量呼吸和/或心肺疾病患者的呼吸困难 疾病。第一阶段的方法将评估在运动中使用 一种计算机系统，患者通过该系统提供自发的评分，然后 与伴随的生理变量水平有关。这样做的目的是 可行性研究的目的是确定 测量呼吸困难的连续方法。研究对象为24名患者 另设慢性阻塞性肺疾病患者24例为对照组。 年龄和性别相匹配的个人。 建议的商业应用： 商业目标是提供呼吸生理学和运动医学领域 用一种连续的方法来测量运动中的呼吸困难。产品将是 世界各地的医生、诊所和医院都可以购买的计算机软件包。

DESCRIPTION (provided by applicant): For patients with respiratory disease the symptom of breathlessness (dyspnea) is the most frequent reason for seeking medical attention. Current methods for measuring breathlessness have patients provide ratings each minute during an incremental exercise test. Such "discrete" methods have limitations: 1) as patients breathe through a mouthpiece, they must point to a number on a scale which can lead to recording errors; 2) in patients with severe impairment only a few ratings of breathlessness are obtained; and 3) information is lost about the progressive nature of breathlessness because patients are asked for ratings at arbitrary time periods rather than when actual changes in breathlessness occur. The long-term objective of this project is to develop a continuous method to measure breathlessness in patients with respiratory and/or cardiopulmonary disease. The Phase I approach will assess breathlessness during exercise using a computer system whereby patients provide spontaneous ratings that are then related to the levels of concomitant physiological variables. The aims of this feasibility study are to establish the reliability and validity of the continuous method for measuring breathlessness. Subjects will be 24 patients with chronic obstructive pulmonary disease and a control group of 24 healthy individuals matched for age and gender. PROPOSED COMMERCIAL APPLICATION: The commercial goal is to privide the areas of respiratory physiology and sports medicine with a continuous method for measuring breathlessness during exercise. The Product will be a computer software package that can be purchased by physicians, clinics and hospitals throughout the world.