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EFFECT OF MEALS ON SERUM DHEA

EFFECT OF MEALS ON SERUM DHEA
膳食对血清 DHEA 的影响
批准号:
6122092
负责人:
FRANK SVEC
金额:
$1.12万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-07-19 至 1999-11-30

项目摘要

项目成果

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中文摘要
翻译
脱氢表雄酮是一种在肾上腺中制造的荷尔蒙,似乎可以保护人们免受心脏病发作。目前,人们对控制血液中这种激素水平的因素知之甚少。刺激肾上腺的一种情况是进餐。因此,预计当一个人进食时,他血液中的脱氢表雄酮水平应该会上升。然而,首席调查员在初步研究中发现,这种水平实际上随着餐食的增加而下降。其他研究表明,胰岛素可以提高脱氢表雄酮从血清中的清除(或清除)。通常认为,血清脱氢表雄酮的下降是由一餐中胰岛素的升高引起的。该项目的目标是通过监测脱氢表雄酮的下降,并将其与标准膳食中胰岛素的增加进行比较,来检验这一假设。
英文摘要
DHEA is a hormone made in the adrenal gland that appears to protect people from heart attacks. At this time little is known about those factors that control the level of this hormone in the blood. One condition that stimulates the adrenal gland is the consumption of a meal. Hence, it was anticipated that when a person ate, his blood level of DHEA should rise. However, the Principal Investigator found in preliminary studies, that the level actually goes down with meals. Others have shown that insulin enhances the clearance (or removal) of DHEA from the serum. It is often reasoned that the decrease in serum DHEA is caused by the rise in insulin of a meal. The goal of this project is to test this hypothesis by monitoring the fall of DHEA and comparing it with the increase in insulin in response to a standard meal.
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LEPTIN, BODY COMPOSITION, ADRENAL AND GONADAL HORMONES
  • 批准号:
    6970781
  • 项目类别:
  • 资助金额:
    $4.6万
  • 财政年份:
    2004
  • 负责人:
    FRANK SVEC
  • 依托单位:
DEHYDROEPIANDROSTERONE-SULFATE AS A BIOMARKER OF SENESCENCE IN MALE NHPS
  • 批准号:
    6970780
  • 项目类别:
  • 资助金额:
    $4.6万
  • 财政年份:
    2004
  • 负责人:
    FRANK SVEC
  • 依托单位:
LEPTIN, BODY COMPOSITION, ADRENAL AND GONADAL HORMONES
  • 批准号:
    6939808
  • 项目类别:
  • 资助金额:
    $5.32万
  • 财政年份:
    2003
  • 负责人:
    FRANK SVEC
  • 依托单位:
DEHYDROEPIANDROSTERONE-SULFATE AS A BIOMARKER OF SENESCENCE IN MALE NHPS
  • 批准号:
    6939707
  • 项目类别:
  • 资助金额:
    $5.32万
  • 财政年份:
    2003
  • 负责人:
    FRANK SVEC
  • 依托单位:
海外基金