课题基金 / 基金详情

ORAL APPLIANCE THERAPY FOR UPPER AIRWAY RESISTANCE SYNDROME

ORAL APPLIANCE THERAPY FOR UPPER AIRWAY RESISTANCE SYNDROME
口腔矫治器治疗上呼吸道阻力综合征
批准号：
6305807
负责人：
David M Rapoport
金额：
$2.1万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6305807
关键词：
assistive device /technology biomedical equipment development clinical research clinical trial phase I evaluation /testing human subject human therapy evaluation polysomnography respiratory airflow disorder sleep disorders syndrome

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中文摘要
翻译
本研究旨在评估口腔矫治器治疗上气道阻力综合征（UARS）的疗效。迄今为止，公认的睡眠呼吸障碍的治疗干预是CPAP或手术。疑似UARS的患者将接受临床夜间多导睡眠图（NPSG）测试以确认诊断，排除其他睡眠障碍的存在并建立基线值。UARS患者将被定制一个口腔矫治器，并接受第二次NPSG，以评估口腔矫治器对UARS的效果。没有打鼾和上气道阻力测量以及患者耐受性将被认为是有效的治疗。
英文摘要
This study will assess the efficacy of oral appliance therapy in the treatment of upper airway resistance sydrome (UARS). To date, the accepted therapeutic interventions for sleep disordered breathing are CPAP or surgery. Patients with suspected UARS will undergo clinical nocturnal polysomnogram (NPSG) testing to confirm the diagnosis , rule out the presence of other sleep disorders and establish baseline values. UARS patients will be custom-fitted with an oral appliance and undergo a second NPSG to evaluate the effect of oral appliance for UARS. An absence of snoring and upper airway resistance measures and patient tolerance will be considered effective therapy.
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