Multidisciplinary Training in Pulmonary Research

申请人摘要 这一机构国家研究服务奖旨在开发 将追求以研究为导向的职业生涯的熟练调查人员 解决与肺部疾病相关的基础和临床问题。培训跨度 各种学科，包括分子和细胞生物学，免疫学， 微生物学、毒理学、生物化学、肺部和重症监护医学， 和新生儿科。有兴趣的博士后学生 年，肺部研究将通过研究生教育接受培训 生物医学科学(GEBS)集群，在通过初选后 考试。支持将在研究生培训的第二年之后开始， 并将持续大约三年，最终获得论文和博士学位。 与肺部疾病相关的学位。博士后医学博士培训候选人将 在完成其专科临床培训后被接受，基于 追求以研究为导向的职业的可能性很高。博士后医学博士 来自成人和儿童肺科、新生儿科的住院医师项目， 免疫学和传染病。拥有博士学位的博士后。 已经掌握了适用于肺部研究的技能的学位也 参加培训的候选人。说教课程、研讨会和会议， 包括研究伦理方面的指导，将补充主要承诺 指导研究经验。受训人员将制定研究方案， 赞助商的密切监督，以及来自 具有适当相关领域专业知识的跨学科教师。 培训将在临床和基础科学实验室进行 罗切斯特大学医学院院系 还有牙科。教职员工拥有研究广泛课题的实验室。 适合训练。主要研究主题包括肺免疫学和 炎症，肺损伤的分子基础，气体和 颗粒物空气污染和呼吸道一氧化氮的产生，以及 导致肺纤维化的机制。

Applicant's Abstract This Institutional National Research Service Award is designed to develop skilled investigators who will pursue research-oriented careers directed at solving basic and clinical problems related to lung diseases. Training spans a variety of disciplines, including molecular and cell biology, immunology, microbiology, toxicology, biochemistry, pulmonary and critical care medicine, and neonatology. Pre-doctoral students who have demonstrated an interest in lung research will be accepted for training through Graduate Education in Biomedical Sciences (GEBS) Clusters, after they have passed their preliminary examinations. Support will begin after the second year of graduate training, and will continue for approximately three years, leading to a thesis and Ph.D. degree related to lung diseases. Post-doctoral M.D. training candidates will be accepted after completion of their subspecialty clinical training, based on a high likelihood of pursuing a research oriented career. Post-doctoral M.D.s come from residency programs in adult and pediatric pulmonology, neonatology, immunology, and infectious diseases. Post-doctoral students with the Ph.D. degree who have developed skills applicable to lung research are also candidates for training. Didactic courses, seminars, and conferences, including instruction in research ethics, will supplement the major commitment to direct research experie'nce. Trainees will develop research protocols with close supervision by their sponsors, and a committee from the interdisciplinary faculty with expertise in appropriately related fields. Training will-take place in laboratories in the clinical and basic science departments and institutes at the University of Rochester School of Medicine and Dentistry. Faculty have laboratories studying a wide range of topics suitable for training. Major research themes include lung immunology and inflammation, the molecular basis of lung injury, effects of gaseous and particulate air pollution, and airway production of nitric oxide, and mechanisms leading to pulmonary fibrosis.