STATISTICAL AND DATA MANAGEMENT CENTER

这份申请是一项建议，作为成人艾滋病临床试验小组(ACTG)的统计和数据管理中心，隶属于罗伯特·斯库利博士领导的ACTG中央小组。我们的总体目标和目标是负责执行委员会的所有统计和数据管理活动，包括：(1)在执行委员会研究报告的设计和分析方面提供统计领导；(2)建立和管理中央数据管理系统；(3)就科学和程序问题以及长期规划与执行委员会的调查人员合作；(4)进行数据库分析；以及(5)就与执行委员会任务相关的问题进行统计研究。为了确保我们的职责及时完成并生产出高质量的产品，我们(1)建立了统计和数据管理中心，每个中心由一个管理结构、与ACTG的科学委员会、内部工作组和支持小组平行的科学部门组成；(2)组建了一支由高素质和经验丰富的统计科学家、程序员、数据经理和其他支持人员组成的员工队伍。

This application is a proposal to serve as the Statistical and Data Management Center of the Adult AIDS Clinical Trials Group (ACTG), in affiliation with the ACTG Central Group headed by Dr. Robert Schooley. Our overall objectives and aims are to be responsible for all statistical and data management activities of the ACTG, including: (1) providing statistical leadership in the design and analysis of ACTG studies; (2) establishing and administering a central data management system; (3) collaborating with ACTG investigators on scientific and procedural issues and on long-range planning; (4) conducting data base analyses, and (5) conducting statistical research on issues central to the ACTG's mission. To ensure that our responsibilities arc completed in a timely manner and yield products of high quality, we have (1) established statistical and data management centers, each consisting of a management structure, scientific sections that parallel the ACTG's scientific committees, internal working groups, and support groups; and (2) assembled a staff of highly-qualified and experienced statistical scientists, programmers, data managers and other support staff.