NEW JERSEY PEDIATRIC AIDS CONSORTIUM

新泽西州儿童艾滋病联合会(NJ-PAC)正在重新竞争RFA AI-96- 001将维持其NIAID儿科和围产期赞助的临床 试验计划。这项计划自1987年起资助，由一个 行政单位、主要围产期组成部分和中心 儿科DAIID实验室调查(CLI) 在NJMS和4个亚单位临床试验站点(儿童医院 新泽西州，大学医院，圣约瑟夫医院和医疗 中心和库珀医院/大学医疗中心)。在这下面 申请，纽瓦克贝斯以色列医疗中心被提议作为一个新的 用于进行儿科和围产期临床试验的亚单位。资金来源 来自NIAID的将通过分包合同，涵盖以下研究人员 UMD/NJMS、新泽西州儿童医院和圣约瑟夫医院 中心，库珀医院/大学医学中心和 建议的NBI将在每位患者的费用报销中得到支持 第一年供资的基数。每个站点都将拥有 从集水区招收艾滋病毒感染者的机会 进入这个全国性的临床试验网络。中华儿科医院 新泽西州和库珀医疗中心将只招收婴儿、儿童和 青年而大学医院，圣约瑟夫和纽瓦克贝思以色列 将参加儿科患者和孕妇的招生 进入围产期临床试验。首席调查员詹姆斯博士 奥莱斯克，全面负责这笔资金的运作 申请。乔治·麦克谢里博士是医疗主任和 儿科首席合作研究员Arlene Bardeguez博士是 首席周边合作研究员黛博拉·斯托姆博士正在研究 协调员；每个临床亚单位都有一名儿科和/或围产儿 调查员、研究护士和药房支持。总体目标是 共招收60名新的艾滋病毒感染患者进入全国 临床试验将包括孕妇，她们的婴儿， 儿童和青年。

The NJ Pediatric AIDS Consortium (NJ-PAC) is recompeting for RFA AI-96- 001 to maintain its NIAID pediatric and perinatal-sponsored Clinical Trials Program. This program, funded since 1987, consists of an administrative unit, primary perinatal component, and Center for Laboratory Investigations (CLI) in the DAIID, Department of Pediatrics at the NJMS and 4 subunit clinical trial sites (Children Hospital of New Jersey, University Hospital, St. Joseph's Hospital and Medical Center, and Cooper Hospital/University Medical Center). Under this application, Newark Beth Israel Medical Center is proposed as a new subunit for conducting pediatric and perinatal clinical trials. Funding from NIAID will be by subcontract, covering research personnel at UMD/NJMS, Children's Hospital of NJ and St. Joseph's Hospital Medical Center, while Cooper Hospital/university Medical Center and the proposed NBI will be supported on a per-patient cost reimbursement basis for the first year of funding. Each site will have the opportunity to enroll HIV infected patients from their catchment area into this national network of clinical trials. Children's Hospital of NJ and Cooper Medical Center will enroll only infants, children and youths while University Hospital, St. Joseph and Newark Beth Israel will participate in enrollment of pediatric patients and pregnant women into perinatal clinical trials. The principal investigator, Dr. James Oleske, is overall responsible for the operation of this funded application. Dr. George McSherry is the medical director director and principal pediatric co-investigator, Dr. Arlene Bardeguez is the principal periantal co-investigator, Dr. Deborah Storm is study coordinator; each clinical subunit has a pediatric and/or perinatal investigator, study nurse, and pharmacy support. The overall goal is to enroll a total of 60 new HIV infected patients into national clinical trials which will include pregnant women, their infants, children and youth.