A prospective, open-label, single-centre/multi-site, randomized clinical trial of a novel maternal microbiological “screen & treat” program compared with normal care for the prevention of preterm birth

2014年，我们的团队发起了世界独一无二的西澳大利亚州早产（PTB）预防倡议，将全州的PTB发病率降低了8%。我们的下一步是试验一项“筛查和治疗”计划，以发现妊娠中期感染肺结核的高风险妇女，并用抗菌药物对她们进行治疗。该研究将涉及6000多名妇女，目的是将自发性肺结核发病率降低30%，如果在全国范围内实施，每年可预防4500例肺结核。

In 2014, our team launched the world-unique Western Australian Preterm Birth (PTB) Prevention Initiative and reduced the rate of PTB state-wide by 8%. Our next step is to trial a “screen & treat” program to detect women in mid-pregnancy at high risk of infection-driven PTB and treat them with antimicrobial medications. The study will involve more than 6000 women and aims to lower the rate of spontaneous PTB rate by 30%, which if applied nationally, may prevent 4500 PTBs each year.