A randomised controlled trial (RCT) of azithromycin versus doxycycline for the treatment of rectal chlamydia infection in men who have sex with men.

直肠衣原体在男同性恋者中非常常见；它可以长期存在，没有导致持续传播的症状。阿奇霉素(1克单次剂量)或7天多西环素(每天两次100毫克)是全球推荐的两种治疗方法。但是，有关于直肠衣原体治疗的担忧，据报道，阿奇霉素治疗失败的比例高达22%。我们将进行一项随机试验，比较这些治疗直肠衣原体的方法，并确定哪种药物效果更好。

Rectal chlamydia is very common among gay men; it can exist for long periods without symptoms leading to ongoing transmission. Azithromycin (1 gram single dose) or 7 days doxycycline (100mg twice daily) are the two recommended treatments globally. But, there is concern about rectal chlamydia treatment with reports of up to 22% failure following azithromycin. We will conduct a randomised trial to compare these treatments for rectal chlamydia and determine which drug works better.