The Influence of Drug Use on Suicide Ideation & Attempts

描述：(申请人提供) 这篇博士前论文研究的具体目的是估计 毒品使用阶段之间的联系(即尼古丁、酒精、大麻和 可卡因)和自杀念头和企图，在一个 最初招募和评估的年轻人的纵向研究 作为流行病学样本。概念框架是由 Kellam和Ensminger(1980)的终身发展概念， Szapocznik和Coatsworth所推崇的社会语境的阐述 (1999年)。这些具体目标将以前瞻性研究设计进行研究。 这包括对2311名参与调查的青少年进行反复的年度评估 从他们进入一年级到14岁。他们现在正在被 在年轻时进行了跟踪调查，对药物紊乱进行了标准化评估， 自杀念头和自杀企图，以及可能的媒介，如抑郁症 和攻击性。用于估计关联的统计模型将 包括具有逻辑联系GLM、生存分析、潜在特质模型以及 潜在的过渡模型。电力分析是提案的一部分， 以及对替代程序、缺点和 平衡优势。

DESCRIPTION: (Provided by Applicant) The specific aims of this predoctoral thesis research is to estimate the association between stages of drug use (i.e., nicotine, alcohol, marijuana and cocaine) and suicide ideation and attempts, within the context of a longitudinal study of young adults who originally were recruited and assessed as an epidemiological sample. The conceptual framework is oriented by the life-span developmental concepts of Kellam and Ensminger (1980), with elaboration of social context of the type espoused by Szapocznik and Coatsworth (1999). These specific aims will be studied with a prospective research design that involved repeated annual assessments of the 2,311 participating youths between their entry to first grade and age 14 years. They are now being followed up as young adults, with standardized assessments of drug disorders, suicide ideation and attempts, as well as possible mediators, e.g. depression and aggression. Statistical models used to estimate the associations will include GLM with a logistic link, survival analysis, latent trait models, and latent transition models. A power analysis is included as part of the proposal, as well as an overview of alternative procedures, weaknesses and counterbalancing strengths.